Hipmunk is a new tool for finding flights and hotels.
I played around with it for a while. For flights it is really easy to use and I really like the way the flight prices and times are displayed in a grid. Makes it easy to see what is available by several criteria including price and departing time.
I tried the hotel search tool also. That worked fine until I tried to use the Heatmap tool. There is a little introductory video that I watched but I still don't understand how to "read" the Heatmap. Might have to play around with it a bit more.
When I look for airfare I typically start with Kayak but Hipmunk might be worth checking out.